Very few people experience side-effects. The reported side-effects include occasional episodes of:

• mild headache
• slight nausea, no vomiting
• soft stool or loose stool with no cramping
• transient increase in anxiety or irritability an hour after initiating treatment, which resolves after an hour or so
• insomnia, which can be corrected by lowering the dose or taking the product not later than midday
• a feeling of sedation, which can be corrected by taking the product as a single 50mg dose at night

NO severe adverse effects have been documented from using Release Sce-Forte™.

The Release Sce formula is Scheduled 0 as a very safe supplement. The mineralized formula was designed according to the “Complimentary medicine D33.7 Western Herbal Combination” The Release Sce range has been formulated by a group of food scientists, pharmacists, researchers and developers. Appointed under strict GMP compliant regulations, these experts manage, formulate and produce all pH7 products. All minerals and plant materials are self-sourced and we ensure raw extraction and quality tests higher than 95%. Every batch is tested, verified and labelled according to the actual active content. All pH7 products are manufactured by GMP principles, and are developed in line with top international standards – a D33.7 Western Herbal Combination.

Long term usage of the minerals at higher doses may have an effect on the body. The Release Sce doses of the minerals are all sufficient to enhance the intended function, but low enough to be safe to use over longer periods of time and also have an additional immune boosting effect. Sceletium tortuosum is non habit-forming and has been used for thousands of years by the The Khoisan people of South Africa. All studies show that it is safer to use over a longer period than a chemical SSRI.

The main ingredient in Release Sce-Forte™ is pure sceletium tortuosum extract. Sceletium tortuosum is proven as a natural and effective selective serotonin re-uptake inhibitor (SSRI). Release Sce-Forte™ contains 50mg pure extract, with between 3.5% and 3.8% standarized alkaloids (actives).

The mood elevating action of sceletium tortuosum is caused by several alkaloids including mesembrine, mesembrenol and tortuosamine which interact with the brain’s dopamine and serotonin receptors. Mesembrine is a major alkaloid present in sceletium tortuosum. Mesembrine has been demonstrated to be a potent serotonin-uptake inhibitor and serotonin releasing agent.

The best time to take Release Sce is early morning with breakfast and, if needed, late afternoon. It is always best to take it before or with a meal.

In May 2019, pH7 Manufacturing (PTY) LTD released Release Sce-Junior™, a delicious, sweet syrup designed for children as young as 1 – 2 years old and effective enough for adults. Due to the South African Health Products Regulatory Authority, SAHPRA (formerly known as the Medicine Control Counsel) regulations, we had to take two key ingredients out of our formula for younger children, namely chromium picolinate and selenium. But in return we have added vitamin C to our new formula.

There have been no confirmed reports of drug interactions. However, because of the neuro-receptor activities of sceletium tortuosum there may be interactions with other pharmacokinetic drugs. People taking any psychiatric drug (including all anti-anxiety drugs, sedatives, hypnotics, anti-depressants and anti-psychotics and so-called “designer” or recreational drugs) or any cardiac medications, are advised not to take sceletium tortuosum-containing products without their medical doctors assistance. As with most supplements and modern drugs, safety in pregnancy for Release Sce has not been established.