Long term usage of the minerals at higher doses may have an effect on the body. The Release Sce doses of the minerals are all sufficient to enhance the intended function, but low enough to be safe to use over longer periods of time and also have an additional immune boosting effect. Sceletium tortuosum is non habit-forming and has been used for thousands of years by the The Khoisan people of South Africa. All studies show that it is safer to use over a longer period than a chemical SSRI.